Research Article
Ligustrazine Inhibits Cartilage Endplate Hypertrophy via Suppression of TGF-β1
Figure 4
LIG suppresses TGF-β1 distribution and expression in CEP tissue of bipedal rats. (a) Immunohistochemical staining demonstrated stronger positive matrix staining for TGF-β1 (brown) in the marginal area in the Veh group compared to that in the Sham group. LIG treatment weakens the positive staining for TGF-β1. (b) Quantitative data of (a). (c) LIG reduced the increased mRNA level of TGF-β1 in bipedal rats by qPCR. Each column represents the mean ± SE, versus Sham, and versus Veh.
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