Research Article

Additive Effect of Qidan Dihuang Grain, a Traditional Chinese Medicine, and Angiotensin Receptor Blockers on Albuminuria Levels in Patients with Diabetic Nephropathy: A Randomized, Parallel-Controlled Trial

Table 2

Patient baseline characteristics.

CharacteristicTreatment group ()Control group () value

Age (y)0.742
Male sex, no. (%) 24 (51.1)22 (50) 0.919
BMI (kg/m2)25.27 ± 2.8824.70 ± 2.85 0.342
Course of DN (y)0.10 (0.10, 1.30)0.20 (0.10, 0.70)0.627
SBP (mmHg)131.00 (124.00, 136.00)133.50 (120.00, 138.00)0.518
DBP (mmHg)80.00 (75.00, 85.00)80.00 (73.00, 85.00)0.378
Heart rate (bpm)80.00 (76.00, 85.00)78.00 (74.25, 82.00)0.115
Albu (mg/24 h)85.30 (66.00, 176.30)90.50 (67.78, 124.68)0.940
TPU (g/24 h)0.20 (0.10, 0.30)0.20 (0.20, 0.30)0.943
A/C (mg/mol)20.70 (11.00, 30.50)19.45 (7.83, 30.63)0.952
FPG (mmol/L)7.40 (6.70, 7.80)7.40 (6.80, 7.80)0.883
2 h PBG (mmol/L)9.52 ± 1.279.58 ± 1.050.877
HbA1c (%)8.92 ± 1.748.78 ± 2.090.717
TG (mmol/L)1.43 (1.15, 2.30)1.55 (0.95, 2.29)0.799
TC (mmol/L)5.06 ± 1.09 5.11 ± 1.020.828
LDL (mmol/L)3.11 ± 0.863.06 ± 1.030.798
HDL (mmol/L)1.20 (0.99, 1.49)1.12 (0.92, 1.64)0.700
BUN (mmol/L)5.46 ± 1.865.28 ± 1.490.605
Scr (μmol/L)63.00 (56.00, 80.00)62.00 (55.00, 87.25)0.694
ALT (μ/L)18.00 (14.00, 27.00)19.50 (15.00, 25.75)0.889
AST (μ/L)20.00 (15.00, 27.00)19.5 (16.25, 24.00)0.769

Data are expressed as the mean ± SD for normal distribution. Nonnormally distributed values are presented as medians (interquartile range). values represent the treatment group versus the control group. BMI, body mass index; DN, diabetic nephropathy; SBP, systolic blood pressure; DBP, diastolic blood pressure; Albu, albuminuria; TPU, total proteinuria; A/C, urinary albumin to creatinine ratio; FPG, fasting plasma glucose; PBG, postprandial blood glucose; TG, triglycerides; TC, total cholesterol; LDL, low density lipoprotein cholesterol; HDL, high density lipoprotein cholesterol; BUN, blood urea nitrogen; Scr, serum creatinine; ALT, alanine transaminase; AST, aspartate transaminase.