Research Article
PGC-1α Mediated Peripheral Nerve Protection of Tongxinluo in STZ-Induced Diabetic Rats
Figure 6
mRNA expression of genes associated with mitochondrial biogenesis of sciatic nerves. The mRNA level of PGC-1α (a), SOD (b), and COX IV (c) of sciatic nerves from all three groups was analyzed by RT-PCR. The expression of these genes in diabetic rats significantly decreased compared to control group (), which was reversed by Tongxinluo treatment in DM+Txl group (, ).
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