Sequential Treatments with Tongsai and Bufei Yishen Granules Reduce Inflammation and Improve Pulmonary Function in Acute Exacerbation-Risk Window of Chronic Obstructive Pulmonary Disease in Rats

Figure 8

Changes in MPO (a1, b1), PMN elastase (a2, b2), IL-1β (a3, b3), TNF-α (a4, b4), IL-6 (a5, b5), and IL-10 (a6, b6) levels in the serum (a) and BALF (b) from sequentially/nonsequentially treated COPD rats. AE: acute exacerbation; BYG: Bufei Yishen Granule; COPD: chronic obstructive pulmonary disease; IL: interleukin; MPO: myeloperoxidase; MXF: moxifloxacin; NS: normal saline; PMN: polymorphonuclear; RW: risk window; TNF: tumor necrosis factor; TSG: Tongsai Granule; STL: salbutamol. . , versus Control group; , versus COPD group; , versus AECOPD group; , versus TSG/NS group; , versus MXF+STL/NS group; , versus TSG/BYG group; , versus MXF+STL/STL group.

(a)

(b)