Sequential Treatments with Tongsai and Bufei Yishen Granules Reduce Inflammation and Improve Pulmonary Function in Acute Exacerbation-Risk Window of Chronic Obstructive Pulmonary Disease in Rats

Figure 9

Representative images of the pathology in lung tissues from rats administered sequential/nonsequential treatments. (a) Control group; (b) chronic obstructive pulmonary disease (COPD) group, (c) acute exacerbation of COPD (AECOPD) group; (d) TSG/NS group; (e) MXF+STL/NS group; (f) TSG/BYG group; (g) MXF+STL/STL group; (h) TSG+MXF+STL/BYG+STL group. H&E stained, magnification: ×100. (i) Mean linear intercept (MLI); (j) mean alveolar numbers (MAN). AE: acute exacerbation; BYG: Bufei Yishen Granule; COPD: chronic obstructive pulmonary disease; MXF: moxifloxacin; NS: normal saline; RW: risk window; TSG: Tongsai Granule; STL: salbutamol. . , versus Control group; , versus COPD group; , versus AECOPD group; , versus TSG/NS group; , versus MXF+STL/NS group; , versus TSG/BYG group; , versus MXF+STL/STL group.

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