Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats

<div>Effect of YSTE on cell proliferation in the prostate in BPH rats. (a) Total prostate protein (30 <i>μ</i>g) was subjected to western blot analysis for identification of PCNA and cyclin D1 protein levels. The <i>β</i>-actin protein concentration was used as an internal control. (b) The number of Ki-67-positive cells in the prostate from BPH rats was determined by immunohistochemistry using anti-Ki-67 (magnification, ×200). NC, negative control; BPH, TP-induced BPH; Fin, administration of finasteride and s.c. injection of TP; YSTE-200, administration of 200 mg/kg/day of YSTE and s.c. injection of TP; YSTE-500, administration of 500 mg/kg/day of YSTE and s.c. injection of TP.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 4

Figure 4: Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats 

Figure 4 | Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats 