Jiang Tang Xiao Ke Granule, a Classic Chinese Herbal Formula, Improves the Effect of Metformin on Lipid and Glucose Metabolism in Diabetic Mice

Table 4

Effect of MET combined with JTXK on hepatic function and mass in DM mice.

Groups	Dose (g/kg)	ALT activity	AST activity	Hepatic weight	Hepatic index
		(U/L)	(U/L)	(g)	(%)
Normal	—	28.33 ± 4.93	23.87 ± 4.06	2.18 ± 0.20	5.02 ± 0.45
DM	—	92.73 ± 13.64	77.61 ± 5.33	4.22 ± 0.45	9.77 ± 0.80
MET	0.19	61.47 ± 9.39	48.37 ± 5.32	3.27 ± 0.42	8.01 ± 0.89
MET/JTXK	0.19/1.75	48.50 ± 7.34	42.93 ± 7.00	2.94 ± 0.44	7.69 ± 1.18
	0.19/3.5	41.80 ± 5.81	36.47 ± 3.40	2.44 ± 0.40	6.59 ± 1.08
	0.19/7	78.70 ± 6.85	69.07 ± 7.81	2.36 ± 0.32	6.27 ± 1.01

⁢ and versus the normal group; and versus the drug-untreated DM group; and versus the MET alone group.