Hataedock Treatment Has Preventive Therapeutic Effects in Atopic Dermatitis-Induced NC/Nga Mice under High-Fat Diet Conditions

Figure 1

Experimental design. Before inducing AD, the extract of Coptidis Rhizoma and Glycyrrhiza uralensis, which is traditionally used in HTD treatment, was administered orally to the HTT group on days 1, 2, and 3. Mice were challenged by DNFB on days 28, 35, and 42. During the experimental period, all groups except the Ctrl group were fed a high-fat diet freely. Ctrl: normal feeding, HF: high-fat diet, HDE: high-fat diet and untreated AD-induced, HTT: high fat diet and Hataedock treated AD-induced, HFD: high-fat diet, HTD: Hataedock, PBS: phosphate-buffered saline, and DNFB: dinitrofluorobenzene.