Research Article

GC-MS Analysis: In Vivo Hepatoprotective and Antioxidant Activities of the Essential Oil of Achillea biebersteinii Afan. Growing in Saudi Arabia

Table 2

Effect of A. biebersteinii essential oil (ABEO) on induced hepatotoxicity-related parameters.

Treatment group ()SGOT (U/L)SGPT (U/L)GGT (U/L)ALP (U/L)Bilirubin (mg/dL)

Normal control79.66 ± 4.4042.83 ± 2.777.58 ± 0.27346.33 ± 9.400.57 ± 0.01
CCl4 only319.33 ± 10.85270.16 ± 21.2319.15 ± 1.19624.83 ± 11.762.84 ± 0.17
ABEO (0.2 mL/kg + CCl4)217.22 ± 9.75176.83 ± 8.1311.08 ± 0.57535.33 ± 12.361.80 ± 0.07
Silymarin (10 mg/kg + CCl4)147.5 ± 10.85118.18 ± 7.489.06 ± 0.35413.81 ± 13.601.29 ± 0.08

All values represent mean ± SEM. ; ; ; ANOVA, followed by Dunnett’s multiple comparison test. As compared with normal group. As compared with CCl4 only group.