Membrane Stabilization and Detoxification of Acetaminophen-Mediated Oxidative Onslaughts in the Kidneys of Wistar Rats by Standardized Fraction of Zea mays L. (Poaceae), Stigma maydis
Table 6
Effect of Zea mays, Stigma maydis ethyl acetate fraction on specific activities of enzymic antioxidant system of acetaminophen-treated rats (, mean ± SEM).
Treatments
Antioxidant enzymes (nmol min−1 mgprotein−1)
SOD
Catalase
Glutathione Rx
Glutathione Px
Sterile placebo (control)
43.12 ± 0.15
33.99 ± 0.11
56.11 ± 0.45
123.15 ± 1.10
APAP treatment
10.11 ± 0.10
13.29 ± 0.12
18.11 ± 0.23
43.66 ± 1.15
200 mg/kg b.w. CSEAF
59.21 ± 0.03
45.35 ± 0.11
55.19 ± 0.20
144.11 ± 1.10
100 mg/kg b.w. CSEAF, then APAP
32.12 ± 0.11
22.76 ± 0.15
30.21 ± 0.25
102.31 ± 1.10
200 mg/kg b.w. CSEAF, then APAP
41.24 ± 0.12
32.99 ± 0.19
53.99 ± 0.23
125.03 ± 1.11
200 mg/kg b.w. vitamin C, then APAP
42.07 ± 0.21
33.09 ± 0.11
56.04 ± 0.35
100.19 ± 1.09
APAP, then 100 mg/kg b.w. CSEAF
32.11 ± 0.12
22.18 ± 0.13
31.14 ± 0.31
98.22 ± 1.15
APAP, then 200 mg/kg b.w. CSEAF
31.99 ± 0.15
31.00 ± 0.13
55.09 ± 0.26
120.11 ± 1.10
APAP, then 200 mg/kg b.w. vitamin C
30.98 ± 0.20
30.01 ± 0.12
33.04 ± 0.35
96.12 ± 1.12
Values with different superscripts for each parameter are significantly different (). APAP: acetaminophen, CSEAF: corn silk ethyl acetate fraction, SOD: superoxide dismutase, Rx: reductase, and Px: peroxidase.
