|
ā | TCM therapeutic action class | TCM therapeutic action subclass | Top three enriched targets | Target function reported by literatures | Average Score |
|
Cluster X | Wind-dampness dispelling | Bone (sinew) strengthening | DNA topoisomerase 1 | Cancer | 0.0144 |
Sodium/glucose cotransporter 1 | Glucose homeostasis | 0.0342 |
Steryl-sulfatase | Immunomodulation | 0.0370 |
Tonifying and replenishing | Qi tonifying | Tyrosine-protein phosphatase nonreceptor type 2 | Immunomodulation | 0.0174 |
Sodium/glucose cotransporter 2 | Glucose homeostasis | 0.0282 |
Sodium/glucose cotransporter 1 | Glucose homeostasis | 0.0321 |
Cough suppressing and panting-calming | Clearing and heat phlegm resolving | Tyrosine-protein phosphatase nonreceptor type 2 | Immunomodulation | 0.0112 |
DNA topoisomerase 1 | Cancer | 0.0236 |
Testosterone 17-beta-dehydrogenase 3 | Reproduction system | 0.0341 |
Tranquilizing | Heat nourishing tranquilizing | Peptidyl-prolyl cis-trans isomerase FKBP1A | Immunomodulation | 0.0077 |
Tyrosine-protein phosphatase nonreceptor type 2 | Immunomodulation | 0.0167 |
Glutamate carboxypeptidase 2 | CNS | 0.0209 |
|
Cluster VII | Heat-clearing medicinal | Heat-clearing and blood cooling | Protein kinase C beta type | Immunomodulation | 0.0100 |
DNA topoisomerase 1 | Cancer | 0.0123 |
Sodium/glucose cotransporter 2 | Glucose homeostasis | 0.0137 |
Hemostatic medicinal | Stasis resolving hemostatic | Tyrosine-protein phosphatase nonreceptor type 2 | Immunomodulation | 0.0089 |
Protein kinase C eta type | Immunomodulation | 0.0182 |
Protein kinase C gamma type | Immunomodulation | 0.0209 |
Tonifying and replenishing | Blood tonifying | Tyrosine-protein phosphatase nonreceptor type 2 | Immunomodulation | 0.0140 |
Protein kinase C beta type | Immunomodulation | 0.0230 |
Protein kinase C eta type | Immunomodulation | 0.0240 |
|
Cluster XII | Parasite destroying, dampness eliminating, and itchiness relieving | ā | Dihydrofolate reductase | Cancer, bacterial infection | 0.0532 |
DNA-dependent protein kinase catalytic subunit | Cancer | 0.0644 |
Tumour necrosis factor | Cancer, bacterial infection | 0.0687 |
|