Research Article

The Effect of Wenxin Keli on the mRNA Expression Profile of Rabbits with Myocardial Infarction

Table 3

Interesting genes associated with immunity and inflammation, neurohumoral system, angiogenesis, and apoptosis.

Effect onGene symbolGene nameAverage (fold change) in WXKL versus model

Immunity and inflammationACKR4Atypical chemokine receptor 4−2.01605730.041537866
CLEC4AC-type lectin domain family 4, member A−3.17453740.010384568
ICAM5Intercellular adhesion molecule 5, telencephalin−6.039340.03805122
CX3CR1Chemokine (C-X3-C motif) receptor 1−5.1964110.048417185
MRC1Mannose receptor, C type 1−4.01259140.013496869
LOC100349667HLA class II histocompatibility antigen, DRB1-1 beta chain-like−3.96183660.033953466
FPR1Formyl peptide receptor 1−3.85572120.015122267
RLA-DR-ALPHAMajor histocompatibility complex, class II, DR alpha−3.57408170.038230587
MS4A4AMembrane-spanning 4-domains, subfamily A, member 4A−3.41016530.015798943
MSR1Macrophage scavenger receptor 1−2.89040140.026199685
HCLS1Hematopoietic cell-specific Lyn substrate 1−2.6447420.023556033
RLA-DMBHistocompatibility antigen DM heterodimer light chain-like−2.4385710.049889226
LY86Lymphocyte antigen 86−2.42697950.037516456
IGDCC4Immunoglobulin superfamily, DCC subclass, member 43.33477450.014958037
IGSF6Immunoglobulin superfamily, member 6−2.21428970.023191037

Neurohumoral factorACEAngiotensin I converting enzyme−2.47937510.037596557
EDN1Endothelin 1−2.76998930.04192766
CRYMMyogenin (myogenic factor 4)4.21027570.04186551
UCNUrocortin2.03027560.021255666

AngiogenesisRSPO3 R-spondin 34.4367980.002975913

ApoptosisCTSCCathepsin C−2.1843060.0108809
TTC5Tetratricopeptide repeat domain 5−3.57529450.015227082

FC, fold change; , value calculated from two double factor variance analyses.