Chamaecyparis obtusa Suppresses Virulence Genes in Streptococcus mutans

Figure 5

Inhibitory effect of C. obtusa essential oil on virulence factor gene expression. S. mutans was cultured and treated with subminimal inhibitory concentration (0.025–0.1 mg/mL) of C. obtusa extract, and real-time polymerase chain reaction (PCR) analysis was performed. The brpA, gbpB, gtfC, and gtfD expressions were significantly inhibited at 0.025 mg/mL of C. obtusa. Each value is expressed as mean ± standard deviation. was determined at when compared with the control group.