Rannasangpei Is a Therapeutic Agent in the Treatment of Vascular Dementia

Figure 4

Effects of RSNP on the Bax and Bcl-2 levels in the hippocampus of VD model induced by 2VO. After completing the behavior test, the hippocampus was segregated and used to assess the expression of Bax and Bcl-2 by Western blot analysis (a). The intensities of Bcl-2 and Bax protein bands were used to determine the Bax/Bcl-2 ratio (b). The transcript levels of Bcl-2 (c) and Bax (d) genes in the hippocampus were also measured to verify the profile of protein expression. All the data were shown as mean ± SD, per group. , compared with the sham-operated group; , compared with the VD model group; , compared with the RSNP-L group. , compared with the RSNP-M group.

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