Modes of Antiviral Action of Chemical Portions and Constituents from Woad Root Extract against Influenza Virus A FM1
Table 2
Inhibitory effect of pure compounds and chemical portions from woad root extract on influenza A FM1 virus attachment.
Groups
OD560
Protection rate (%)
1 : 2
1 : 4
1 : 8
1 : 16
1 : 2
1 : 4
1 : 8
1 : 16
CB (50 μg/mL)
1.940 ± 0.262
1.665 ± 0.058
1.599 ± 0.161
1.368 ± 0.210
201.267
161.455
151.973
118.458
Epigoitrin (50 μg/mL)
2.192 ± 0.108
1.980 ± 0.246
1.833 ± 0.049
1.639 ± 0.347
237.749
207.058
185.849
157.763
PEP portion (1 mg/mL)
2.437 ± 0.190
2.340 ± 0.123
2.020 ± 0.319
1.695 ± 0.041
273.218
259.175
212.921
165.798
PEP + ALK + OA (1 mg/mL)
2.043 ± 0.072
2.055 ± 0.009
1.743 ± 0.282
1.599 ± 0.069
216.178
217.988
172.819
151.900
Ribavirin (100 μg/mL)
1.614 ± 0.093
1.736 ± 0.307
1.441 ± 0.001
1.279 ± 0.018
154.144
171.734
129.099
105.646
Virus control
0.549 ± 0.690
Cell control
1.24 ± 0.675
PEP: phenylpropanoids portion; PEP + ALK + OA: the mixtures of phenylpropanoids, alkaloids, and organic acid portions. Cell control: normal cells without virus infection and drug treatments. Virus control: cells infected with influenza A FM1 virus. Data of OD560 was mean ± SD. The asterisks indicate a significant difference between the test samples and the virus control according to Student’s t-test. .
