Review Article

Benefits of Whole-Body Vibration, as a Component of the Pulmonary Rehabilitation, in Patients with Chronic Obstructive Pulmonary Disease: A Narrative Review with a Suitable Approach

Table 3

Level of evidence and outcomes of reviewed papers.

Level of evidenceAuthorsSampleProtocols and outcome measures WBV findings

IIGreulich et al., 2014 [23]N = 40 (26 males and 14 females)
IG n = 20
IG age = 66 ± 10 years
CG n = 20
CG age = 70 ± 10 years
IG: standard physiotherapy with WBV
CG: standard physiotherapy
Duration: during inpatient admission
Outcomes: CRT, 6MWT, QoL, and serum markers
Improved CRT, 6MWT, and QoL 
Increased expression of the TFPP receptor gamma coactivator-1-α and levels of irisin
Decreased serum interleukin-8

IIPleguezuelos et al., 2013 [26]N = 51 males
IG n = 26
IG age = 73 ± 14 years
CG n = 25
CG age = 74 ± 10 years
IG: WBV
CG: lifestyle education
Duration: 6 weeks
Outcomes: IKFET lower limb performance, 6MWT, and pulmonary muscular assessment with MIP and MEP
No differences for IKFET
Improved 6MWT, MIP, and MEP

IIGloeckl et al., 2012 [27]N = 72 (37 males and 35 females)
IG n = 36
IG age = 64 ± 11 years
CG n = 36
CG age = 65 ± 7 years
IG: WBV with dynamic squats
CG: dynamic squats
Duration: 3 weeks
Outcomes: 6MWT, sit-to-stand test, and QoL
Improvement in 6MWT, sit-to-stand test
No difference between groups for QoL

III-1 Braz Júnior et al., 2015 [22]N = 11 (8 males and 3 females)
Age: 63 ± 9 years
Design: crossover with washout
IG: WBV
CG: No intervention
Duration: 12 weeks
Outcomes: 6MWT, IPE, and QoL
Improved 6MWT and QoL
No difference among groups for IPE

III-1Furness et al., 2014 [24]N = 16 (12 males and 4 females)
Age: 72 ± 9 years
Design: crossover with washout
IG: WBV
CG: SWBV
Duration: 6 weeks
Outcomes: Borg CR-10, heart rate, saturation of oxygen, TUG test, 5-chair stand test, and gait velocity
No exacerbations were reported during the WBV or SWBV interventions. After improved TUG test, 5-chair stand test and gait velocity
No meaningful difference among groups for Borg CR-10, heart rate, and saturation of oxygen

III-1 Furness et al., 2013 [25]N = 17
Age: 69 ± 8 years
Design: crossover with washout
IG: WBV
CG: SWBV
Duration: 1 session
Outcomes: Borg CR-10, heart rate, and saturation of oxygen
No meaningful differences among groups

IG: intervention group; CG: control group; CRT: chair rising test; 6MWT: 6-minute walk test; QoL: quality of life; IKFET: isokinetic knee flexor/extensor testing; MIP: maximum inspiratory pressure; MEP: maximum expiratory pressure; IPE: index of perceived exertion; SWBV: sham whole-body vibration.