Effect of Kuijie Granule on the Expression of TGF-β/Smads Signaling Pathway in Patients with Ulcerative Colitis

Figure 6

Study flow chart of Kuijie Granule for ulcerative colitis. In this study, we take steps as follows: (1) determine the diagnostic criteria for UC; (2) collect the cases and score the main symptoms; (3) collect the colonic pathological tissue to detect and analyze the expression of TGF-β/Smads, which include TGF-β1, TGF-βRII, Smad2, Smad4, Smad6, and Smad7; (4) treat UC patients with Kuijie Granule for 60 days; (5) repeat steps (2) and (3); (6) compare the main symptoms scores and TGF-β/Smads expression before and after Kuijie Granule treatment; (7) get the conclusions.