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Evidence-Based Complementary and Alternative Medicine
Volume 2016, Article ID 2680409, 14 pages
http://dx.doi.org/10.1155/2016/2680409
Review Article

The Therapeutic Potential of Rosemary (Rosmarinus officinalis) Diterpenes for Alzheimer’s Disease

Pharmacognosy Research Laboratories & Herbal Analysis Services UK, Chatham-Maritime, Kent ME4 4TB, UK

Received 18 October 2015; Accepted 28 December 2015

Academic Editor: Ki-Wan Oh

Copyright © 2016 Solomon Habtemariam. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [27 citations]

The following is the list of published articles that have cited the current article.

  • Anna Dzimitrowicz, Sara Berent, Agata Motyka, Piotr Jamroz, Konrad Kurcbach, Wojciech Sledz, and Pawel Pohl, “Comparison of the characteristics of gold nanoparticles synthesized using aqueous plant extracts and natural plant essential oils of Eucalyptus globulus and Rosmarinus officinalis,” Arabian Journal of Chemistry, 2016. View at Publisher · View at Google Scholar
  • Nicolás M. Vázquez, Graciela Fiorilli, Paulo A. Cáceres Guido, and Silvia Moreno, “Carnosic acid acts synergistically with gentamicin in killing methicillin-resistant Staphylococcus aureus clinical isolates,” Phytomedicine, 2016. View at Publisher · View at Google Scholar
  • Mohamed A. El-Esawi, Hosam O. Elansary, Nader A. El-Shanhorey, Amal M. E. Abdel-Hamid, Hayssam M. Ali, and Mohamed S. Elshikh, “Salicylic Acid-Regulated Antioxidant Mechanisms and Gene Expression Enhance Rosemary Performance under Saline Conditions,” Frontiers in Physiology, vol. 8, 2017. View at Publisher · View at Google Scholar
  • N.S.L. Perry, R. Menzies, F. Hodgson, P. Wedgewood, M.-J.R. Howes, H.J. Brooker, K.A. Wesnes, and E.K. Perry, “A randomised double-blind placebo-controlled pilot trial of a combined extract of sage, rosemary and melissa, traditional herbal medicines, on the enhancement of memory in normal healthy subjects, including influence of age,” Phytomedicine, 2017. View at Publisher · View at Google Scholar
  • A.E. Kholif, O.H. Matloup, T.A. Morsy, M.M. Abdo, A. Abu Elella, U.Y. Anele, and K.C. Swanson, “Rosemary and lemongrass herbs as phytogenic feed additives to improve efficient feed utilization, manipulate rumen fermentation and elevate milk production of Damascus goats,” Livestock Science, 2017. View at Publisher · View at Google Scholar
  • Solomon Habtemariam, “Protective effects of caffeic acid and the Alzheimer’s brain: An update,” Mini-Reviews in Medicinal Chemistry, vol. 17, no. 8, pp. 667–674, 2017. View at Publisher · View at Google Scholar
  • O.V. Filiptsova, L.V. Gazzavi-Rogozina, I.A. Timoshyna, O.I. Naboka, Ye.V. Dyomina, and A.V. Ochkur, “The effect of the essential oils of lavender and rosemary on the human short-term memory,” Alexandria Journal of Medicine, 2017. View at Publisher · View at Google Scholar
  • O.V. Filiptsova, L.V. Gazzavi-Rogozina, I.A. Timoshyna, O.I. Naboka, V. Dyomina Ye, and A.V. Ochkur, “The essential oil of rosemary and its effect on the human image and numerical short-term memory,” Egyptian Journal of Basic and Applied Sciences, 2017. View at Publisher · View at Google Scholar
  • Andrea del Pilar Sánchez-Camargo, and Miguel Herrero, “Rosemary (Rosmarinus officinalis) as a functional ingredient: recent scientific evidence,” Current Opinion in Food Science, vol. 14, pp. 13–19, 2017. View at Publisher · View at Google Scholar
  • M. Belmouhoub, I. Chebout, and M. Iguer-ouada, “Antidiabetic and anti-hypercholesterolemic effects of flavonoid-rich fractions of Rosmarinus officinalis in streptozotocin-induced diabetes in mice,” Phytothérapie, 2017. View at Publisher · View at Google Scholar
  • Severina Pacifico, Simona Piccolella, Annamaria Lettieri, Paola Nocera, Flavia Bollino, and Michelina Catauro, “A metabolic profiling approach to an Italian sage leaf extract (SoA541) defines its antioxidant and anti-acetylcholinesterase properties,” Journal of Functional Foods, vol. 29, pp. 1–9, 2017. View at Publisher · View at Google Scholar
  • Nasiara Karim, Imran Khan, Abeer Abdelhalim, Heba Abdel-Halim, and Jane R. Hanrahan, “Molecular docking and antiamnesic effects of nepitrin isolated from Rosmarinus officinalis on scopolamine-induced memory impairment in mice,” Biomedicine & Pharmacotherapy, vol. 96, pp. 700–709, 2017. View at Publisher · View at Google Scholar
  • Pedro S. Pereira, Ana J. Maia, Saulo R. Tintino, Cícera Datiane de M. Oliveira-Tintino, Iranir Sâmya de S. Raulino, Maria C. Vega, Miriam Rolón, Cathia Coronel, Luiz Marivando Barros, Antônia Eliene Duarte, Irwin R.A. de Menezes, Henrique D.M. Coutinho, and Teresinha G. da Silva, “Trypanocide, antileishmania and cytotoxic activities of the essential oil from Rosmarinus officinalis L in vitro,” Industrial Crops and Products, vol. 109, pp. 724–729, 2017. View at Publisher · View at Google Scholar
  • Abhinav Anand, Albert Anosi Patience, Neha Sharma, and Navneet Khurana, “The present and future of pharmacotherapy of Alzheimer’s disease: a comprehensive review,” European Journal of Pharmacology, 2017. View at Publisher · View at Google Scholar
  • Noriko Shinjyo, and Julia Green, “Are sage, rosemary and lemon balm effective interventions in dementia? A narrative review of the clinical evidence,” European Journal of Integrative Medicine, vol. 15, pp. 83–96, 2017. View at Publisher · View at Google Scholar
  • Taiwo Olayemi Elufioye, Tomayo Ireti Berida, and Solomon Habtemariam, “Plants-Derived Neuroprotective Agents: Cutting the Cycle of Cell Death through Multiple Mechanisms,” Evidence-Based Complementary and Alternative Medicine, vol. 2017, pp. 1–27, 2017. View at Publisher · View at Google Scholar
  • Andrés Eduardo Ortíz-Ardila, Crispín Astolfo Celis-Zambrano, María Ximena Rodríguez-Bocanegra, Jorge Robles-Camargo, Jennifer Paola Correa-Cuadros, and Luis Gonzalo Sequeda-Castañeda, “Antioxidant and antimicrobial capacity Cecropia mutisiana Mildbr. (Cecropiaceae) leave extracts,” Emirates Journal of Food and Agriculture, vol. 29, no. 1, pp. 25–35, 2017. View at Publisher · View at Google Scholar
  • Gema Nieto, Gaspar Ros, and Julián Castillo, “Antioxidant and Antimicrobial Properties of Rosemary (Rosmarinus officinalis, L.): A Review,” Medicines, vol. 5, no. 3, pp. 98, 2018. View at Publisher · View at Google Scholar
  • M. Belmouhoub, I. Chebout, and M. Iguer-ouada, “ Antidiabetic and anti-hypercholesterolemic effects of flavonoid-rich fractions of Rosmarinus officinalis in streptozotocin-induced diabetes in mice ,” Phytothérapie, vol. 16, no. 4, pp. 204–210, 2018. View at Publisher · View at Google Scholar
  • Emmanuel Tiyo Ayikobua, Ibrahim Semuyaba, Daniel Ejike Eze, Muhamudu Kalange, Mariam Nansunga, Alfred Omachonu Okpanachi, and Abass Alao Safiriyu, “ Combined Donepezil and Ethanolic Extract of Propolis Improved Memory Better Than Donepezil and Propolis Monotherapy in Wild Type Drosophila melanogaster ,” Evidence-Based Complementary and Alternative Medicine, vol. 2018, pp. 1–5, 2018. View at Publisher · View at Google Scholar
  • Giovanna Felipe Cavalcante e Costa, Hisao Nishijo, Leonardo Ferreira Caixeta, and Tales Alexandre Aversi-Ferreira, “The Confrontation between Ethnopharmacology and Pharmacological Tests of Medicinal Plants Associated with Mental and Neurological Disorders,” Evidence-Based Complementary and Alternative Medicine, vol. 2018, pp. 1–27, 2018. View at Publisher · View at Google Scholar
  • Ludy C. Pabón-Baquero, Ángela María Otálvaro-Álvarez, Margarita Rosa Rendón Fernández, and María Patricia Chaparro-González, “Plant Extracts as Antioxidant Additives for Food Industry,” Antioxidants in Foods and Its Applications, 2018. View at Publisher · View at Google Scholar
  • Joana M Andrade, Célia Faustino, Catarina Garcia, Diogo Ladeiras, Catarina P Reis, and Patrícia Rijo, “ Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity ,” Future Science OA, pp. FSO283, 2018. View at Publisher · View at Google Scholar
  • Solomon Habtemariam, “Molecular Pharmacology of Rosmarinic and Salvianolic Acids: Potential Seeds for Alzheimer’s and Vascular Dementia Drugs,” International Journal of Molecular Sciences, vol. 19, no. 2, pp. 458, 2018. View at Publisher · View at Google Scholar
  • Alaa A. Ahmed, Ehab Tousson, and Mohamed F. Bayomy, “Rosemary extract modulates fertility potential, DNA fragmentation, injury, KI67 and P53 alterations induced by etoposide in rat testes,” Biomedicine and Pharmacotherapy, vol. 98, pp. 769–774, 2018. View at Publisher · View at Google Scholar
  • Solomon Habtemariam, “Iridoids and Other Monoterpenes in the Alzheimer’s Brain: Recent Development and Future Prospects,” Molecules, vol. 23, no. 1, pp. 117, 2018. View at Publisher · View at Google Scholar
  • Solomon Habtemariam, “The brain-derived neurotrophic factor in neuronal plasticity and neuroregeneration: new pharmacological concepts for old and new drugs,” Neural Regeneration Research, vol. 13, no. 6, pp. 983, 2018. View at Publisher · View at Google Scholar