The Multifunctional Effects of Nobiletin and Its Metabolites In Vivo and In Vitro

Figure 4

The structures of NOB metabolites, including NOB (1), 3′-demethylnobiletin (2), 4′-demethylnobiletin (3), 3′,4′-didemethylnobiletin (4), 5-demethylnobiletin (5), 5,3′-didemethylnobiletin (6), 5,4′-didemethylnobiletin (7), and 5,3′,4′-tridemethylnobiletin (8).