Spatholobus suberectus Column Extract Inhibits Estrogen Receptor Positive Breast Cancer via Suppressing ER MAPK PI3K/AKT Pathway

Figure 6

Western blot analysis showing that expression levels of ERK1/2, p-ERK1/2, AKT, p-AKT, PI3K, p-PI3K, and p-mTOR were significantly inhibited in the MCF-7 cells treated with SSCE (80 μg/ml, 160 μg/ml, and 320 μg/ml) in a concentration-dependent manner. The expression of mTOR had no obvious association with the SSCE concentration.