Effect of Amino Acids on the Generation of Ginsenoside Rg3 Epimers by Heat Processing and the Anticancer Activities of Epimers in A2780 Human Ovarian Cancer Cells

Figure 2

Changes in the effects of Panax ginseng extract on A2780 cell proliferation after heat processing with or without amino acids. (a) Cells were treated with nontreated or heat-processed Panax ginseng extract with or without amino acids at different concentrations (100, 250, and 500 μg/mL) for 24 h. (b) Cells were treated with ginsenoside 20(S)-Rg3 or ginsenoside 20(R)-Rg3 at different concentrations (12.5, 25, 50, 100, and 200 μg/mL) for 24 h. Relative cell proliferation was measured by the CCK-8 assay. Each value represents the mean ± SD of three independent experiments. compared with nontreated value.

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