Effect of Amino Acids on the Generation of Ginsenoside Rg3 Epimers by Heat Processing and the Anticancer Activities of Epimers in A2780 Human Ovarian Cancer Cells

Table 1

Changes in contents of ginsenosides (μg/mg).

Ginsenosides	Re	Rb1	Rc	Rb2	Rd	20(S)-Rg3	20(R)-Rg3	Rk1	Rg5
Nontreated	26.1	35.0	15.1	19.7	4.1	—	—	—	—
Heat	2.0	1.4	7.8	3.4	12.1	31.6	20.5	7.3	13.9
Heat/glutamine	—	—	—	—	—	7.4	30.4	14.1	48.1
Heat/leucine	—	—	—	—	—	1.8	42.7	11.7	35.1
Heat/valine	4.5	5.1	2.0	8.9	1.0	41.8	10.3	8.5	18.0
Heat/arginine	—	10.6	0.4	7.7	—	38.5	11.0	10.4	21.3
Heat/alanine	3.7	5.5	2.3	9.4	—	39.0	12.7	8.2	18.0