Study on the Mechanism Underlying the Regulation of the NMDA Receptor Pathway in Spinal Dorsal Horns of Visceral Hypersensitivity Rats by Moxibustion

Figure 5

The differences in the expression of NR1 ((a) and (d)), NR2B ((f)–(i)), and PKCε ((k)–(n)) in spinal cord were statistically significant between all groups () ((e), (j), and (o)). The least significant difference (LSD) -test was performed for pairwise comparison, and the results showed that the expression of NR1, NR2B, and PKCε in the model group significantly increased compared to the normal group () ((b), (g), and (l)). Compared to the model group, the expression of NR1, NR2B, and PKCε in the moxibustion group ((d), (i), and (n)) and the Ro 25-6981 group ((c), (h), and (m)) significantly decreased () ((e), (j), and (o)). Compared to the normal group, ; compared to the model group, . The comparison between the moxibustion group and the Ro 25-6981 group did not show a significant difference () (magnification 200).