Reproductive Toxicity of Zishen Yutai Pill in Rats: The Fertility and Early Embryonic Development Study (Segment I)
Table 1
Effects of Zishen Yutai Pill on the fertility.
Terms
Vehicle control group ()
Positive control group ()
Zishen Yutai Pill-treated groups
Low dose-treated group (3 g/kg/d, )
Moderate dose-treated group (6 g/kg/d, )
High dose-treated group (12 g/kg/d, )
Females cohabited ()
25
25
25
25
25
Females copulated ()
22
24
25
23
23
Females pregnant ()
20
23
25
21
22
Copulation index (%)
88
96
100
92
92
Fecundity index (%)
90.9
95.8
100
91.3
95.7
Fertility index (%)
80
92
100
84
88
Days of mating period (d)
2.82 ± 1.01
2.92 ± 0.88
2.52 ± 0.92
2.70 ± 1.11
2.74 ± 2.22
Copulation index (%): (number of females copulated/number of females cohabited) × 100. Fecundity index (%): (number of females pregnant/number of females copulated) × 100. Fertility index (%): (number of females pregnant/number of females cohabited) × 100.
