Diabetic Osteoporosis: A Review of Its Traditional Chinese Medicinal Use and Clinical and Preclinical Research

Table 4

TCM prescriptions in the treatment of DOP animals.

TCM compound prescription name	Animal model	Administration route, duration, and dosage	Reference
Bushen Zhuanggu capsule; 2	Alloxan (120 mg/kg, twice every other day)	i.g. (8, 16 and 32 g/kg) for 8 weeks	[39]
Shenxiaokang concentrated pill; 9	STZ (25 mg/kg), once a day for 5 days	i.g. (1.58 g/200 g) for 7 weeks	[40]
Bushen Jianpi Huoxue decoction; 8	high fat diet for 4 weeks, i.p. of STZ (30 mg/kg)	i.g. (15 g/kg) for 12 weeks	[41]
Shuanghuang Yigu formula	i.p. of STZ (50 mg/kg) combined with OVX	i.g. (11.5 g/kg) for 10 weeks	[42]
Tangshukang capsule	i.p. of STZ (60 mg/kg)	i.g. (15 g/kg) for 12 weeks	[43]
Bushen Zhuanggu capsule	i.p. of alloxan (120 mg/kg, twice every other day)	i.g (8, 16 and 32 g/kg) for 7 weeks	[44]
Qianggubao	i.p. of alloxan (120 mg/kg, twice every other day)	i.g (1 mL/100 g) for 12 weeks	[45]

Radix Rehmanniae Preparata and Carapax et Plastrum Testudinis (dosage information is not available).
Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Fructus Corni, Poria, Rhizoma Alismatis, Pericarpium Citri Reticulatae, Radix Astragali, and Hirudo (dosage information is not available).
Radix Rehmanniae Preparata, Cortex Eucommiae, Radix Astragali, Fructus Lycii, Colla Cornus Cervi (melting in boiled water), Radix et Rhizoma Salviae Miltiorrhizae, Rhizoma Anemarrhenae, and Radix Cyathulae (dosage information is not available).
Os Draconis, Radix Rehmanniae Preparata, Radix Astragali, Cortex Eucommiae, Radix Dipsaci, Rhizoma Drynariae, Fructus Lycii, Fructus Corni, Poria, Radix Angelicae Sinensis, Radix Cyathulae, Herba Artemisiae Anomalae (dosage information is not available).
TCM names and dosage information are not available.
TCM names and dosage information are not available.
Radix Astragali, Herba Dendrobii, Radix et Rhizoma Salviae Miltiorrhizae, Cortex Eucommiae, Fructus Psoraleae, Fructus Corni, Rhizoma Dioscoreae, Rhizoma Drynariae, Colla CornusCervi (melting in boiled water), and Concha Ostreae (dosage information is not available).