Chinese Herbal Mixture, Tien-Hsien Liquid, Induces G2/M Cycle Arrest and Radiosensitivity in MCF-7 Human Breast Cancer Cells through Mechanisms Involving DNMT1 and Rad51 Downregulation

Figure 2

THL arrested the cell cycle of MCF-7 cells in G2/M phase. MCF-7 cells were treated with increasing concentrations of THL (0.75–6 mg/mL) or PBS only, for 72 h, and the cell cycle distribution was analyzed by flow cytometry. THL increased the percentage of G2/M phase in a dose-dependent manner. The percentage of cells in different phases of the cell cycle is shown in Table 1.