DNA Protection against Oxidative Damage Using the Hydroalcoholic Extract of Garcinia mangostana and Alpha-Mangostin

Figure 1

Genotoxic activity measured by Comet assay of human leukocytes: HEGM treated cells (final concentration of 10 to 640 μg/mL, 1 h, 37°C), DMSO (negative control, 7 mM, 1 h, 37°C), or H₂O₂ (positive control, 1 mM, 1 h, 37°C). Error bars represent mean ± SD of 3 independent experiments. The analysis of variance nonparametric (ANOVA) and Tukey’s test used to compare means. DMSO-induced DNA damage (basal) was subtracted from HEMG-induced DNA damage. .