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Evidence-Based Complementary and Alternative Medicine
Volume 2016, Article ID 3430405, 8 pages
http://dx.doi.org/10.1155/2016/3430405
Research Article

DNA Protection against Oxidative Damage Using the Hydroalcoholic Extract of Garcinia mangostana and Alpha-Mangostin

1Laboratório de Biologia de Fungos, Centro de Biotecnologia, Universidade Estadual de Santa Cruz (UESC), Rodovia Jorge Amado, km 16, 45662900 Ilhéus, BA, Brazil
2Laboratório de Farmacogenômica e Epidemiologia Molecular, Universidade Estadual de Santa Cruz (UESC), Rodovia Jorge Amado, km 16, 45662900 Ilhéus, BA, Brazil
3Laboratório de Desenvolvimento de Vacinas, Instituto de Ciências Biomédicas, Departamento de Microbiologia, Universidade de São Paulo, São Paulo, SP, Brazil
4Genotox-Royal, Universidade Federal do Rio Grande do Sul (UFRGS), Avenida Bento Gonçalves, 9500/Setor 4-Pred 43.421/S113, 91501970 Porto Alegre, RS, Brazil
5Laboratório de Imunofarmacologia, Universidade Federal de Mato Grosso (UFMT), Avenida Fernando Corrêa da Costa, n° 2367, Boa Esperança, 78060900 Cuiabá, MT, Brazil

Received 27 October 2015; Accepted 31 January 2016

Academic Editor: Rainer W. Bussmann

Copyright © 2016 Ronaldo Carvalho-Silva et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary material contains additional data about the instrumentation and HPLC conditions; quantification of a-mangostin in G. mangostana extracts; details about measuring antioxidant activity with DPPH and cell viability test by trypan blue, as well as exemplary figures of Comet assay, micronuclei assay, antioxidant, and cell viability test.

  1. Supplementary Material