Hydroalcoholic Extract from Inflorescences of Achyrocline satureioides (Compositae) Ameliorates Dextran Sulphate Sodium-Induced Colitis in Mice by Attenuation in the Production of Inflammatory Cytokines and Oxidative Mediators
Table 4
Effects of HEAS on lenght and weight of colon, and on weight of spleen and liver of DSS-induced colitic mice.
Treatment
Colon length (mm)
Colon weight (g/100 g)
Spleen weight (g/100 g)
Liver weight (g/100 g)
Non-colitic
Vehicle
102.3 ± 3.7
1.73 ± 0.07
0.41 ± 0.02
4.32 ± 0.29
Colitic
Vehicle
62.5 ± 4.0
0.92 ± 0.11
0.62 ± 0.06
4.48 ± 0.14
Colitic
5-ASA (100 mg/kg)
84.0 ± 3.9
1.15 ± 0.06
0.41 ± 0.03
4.56 ± 0.16
Colitic
HEAS (1 mg/kg)
72.5 ± 5.1
1.10 ± 0.04
0.48 ± 0.04
4.53 ± 0.19
Colitic
HEAS (10 mg/kg)
81.8 ± 3.7
0.95 ± 0.01
0.53 ± 0.04
4.47 ± 0.25
Colitic
HEAS (100 mg/kg)
84.0 ± 3.1
1.49 ± 0.14
0.49 ± 0.01
4.70 ± 0.38
versus non-colitic group; versus colitic group; versus colitic group.
