Acute and Subchronic Oral Toxicity Evaluation of Aqueous Root Extract of Dicoma anomala Sond. in Wistar Rats

Table 3

Haematological data for male rats given aqueous root extracts of Dicoma anomala for 90 days.

Parameters	Unit	Dose (mg/kg/day)
		Control	125	250	500
RBC	millions/µL	8.42 ± 0.10	9.44 ± 0.01	9.3 ± 0.05	9.18 ± 0.02
Haemoglobin	g/dL	16.4 ± 0.01	17.6 ± 0.02	16.9 ± 0.01	16.9 ± 0.01
Haematocrit	L/L	0.55 ± 0.05	0.61 ± 0.01	0.58 ± 0.02	0.59 ± 0.00
MCV	fL	65.00 ± 0.00	64.00 ± 0.00	62.00 ±0.00	64.00 ± 0.00
MCH	pg	19.00 ± 0.01	19.00 ± 0.01	18.00 ± 0.01	19.00 ± 0.01
MCHC	g/dL	30.00 ± 0.10	29.00 ± 0.10	29.00 ± 0.10	29.00 ± 0.10
RDW	fL	12.60 ± 0.01	13.40 ± 0.10	14.00 ± 0.00	14.10 ± 0.2
WBC	thous/µL	5.80 ± 0.02	6.50 ± 0.01	6.40 ± 0.02	6.90 ± 0.02
Neutrophils	×10^9/L	0.22 ± 0.00	0.46 ± 0.01	0.51 ± 0.02	0.62 ± 0.01
Lymphocytes	%	4.58 ± 0.10	4.45 ± 0.20	4.37 ± 0.20	4.89 ± 0.10
Monocytes	%	0.92 ± 0.00	1.43 ± 0.01	1.38 ± 0.01	1.28 ± 0.02
Eosinophils	×10^9/L	0.07 ± 0.00	0.16 ± 0.02	0.09 ± 0.00	0.08 ± 0.00
Basophils	×10^9/L	0.01 ± 0.00	0.02 ± 0.00	0.03 ± 0.01	0.02 ± 0.01
Platelet	thous/L	979.00 ± 0.50	803.00 ± 0.03	701.00 ± 0.10	754.00 ± 0.49

Values are presented as mean ± SEM ().
Significantly different compared to control at .