Acute and Subchronic Oral Toxicity Evaluation of Aqueous Root Extract of Dicoma anomala Sond. in Wistar Rats

Table 4

Haematological data for female rats given aqueous root extracts of Dicoma anomala for 90 days.

Parameters	Unit	Dose (mg/kg/day)
		Control	125	250	500
RBC	millions/µL	7.45 ± 0.10	7.44 ± 0.01	7.53 ± 0.05	7.88 ± 0.02
Haemoglobin	g/dL	14.41 ± 0.01	13.96 ± 0.02	15.09 ± 0.01	15.19 ± 0.01
Haematocrit	L/L	0.50 ± 0.05	0.49 ± 0.01	0.56 ± 0.02	0.59 ± 0.00
MCV	fL	61.00 ± 0.00	60.00 ± 0.00	62.00 ±0.00	63.00 ± 0.00
MCH	pg	16.00 ± 0.01	17.00 ± 0.01	17.00 ± 0.01	18.00 ± 0.01
MCHC	g/dL	27.00 ± 0.10	27.00 ± 0.10	28.00 ± 0.10	28.00 ± 0.10
RDW	fL	10.60 ± 0.01	11.40 ± 0.10	11.09 ± 0.00	11.91 ± 0.2
WBC	thous/µL	5.80 ± 0.02	6.30 ± 0.01	6.70 ± 0.02	6.91 ± 0.02
Neutrophils	×10^9/L	0.12 ± 0.00	0.16 ± 0.01	0.15 ± 0.02	0.16 ± 0.01
Lymphocytes	%	4.08 ± 0.10	4.05 ± 0.20	4.07 ± 0.20	4.80 ± 0.10
Monocytes	%	0.73 ± 0.00	0.93 ± 0.01	1.08 ± 0.01	1.12 ± 0.02
Eosinophils	×10^9/L	0.09 ± 0.00	0.12 ± 0.02	0.08 ± 0.00	0.08 ± 0.00
Basophils	×10^9/L	0.01 ± 0.00	0.02 ± 0.00	0.03 ± 0.01	0.02 ± 0.01
Platelet	thous/L	1007.00 ± 0.50	893.00 ± 0.03	871.00 ± 0.10	944.00 ± 0.49

Values are presented as mean ± SEM ().
Significantly different compared to control at .