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Evidence-Based Complementary and Alternative Medicine
Volume 2016 (2016), Article ID 3632168, 10 pages
http://dx.doi.org/10.1155/2016/3632168
Research Article

Repeated Electroacupuncture Persistently Elevates Adenosine and Ameliorates Collagen-Induced Arthritis in Rats

1Department of Acupuncture, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China
2Chengdu Integrated Traditional Chinese and Western Medicine Hospital, Chengdu, Sichuan 610000, China
3Department of Pathology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China
4Department of Anesthesia, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China
5Department of Neurobiology and Acupuncture Research, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China

Received 12 October 2015; Accepted 6 January 2016

Academic Editor: Chang-Gue Son

Copyright © 2016 Tian-shen Ye et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. D. Harris Jr., “Rheumatoid arthritis. Pathophysiology and implications for therapy,” The New England Journal of Medicine, vol. 322, no. 18, pp. 1277–1289, 1990. View at Publisher · View at Google Scholar · View at Scopus
  2. W. B. van den Berg, “Animal models of arthritis. What have we learned?” Journal of Rheumatology Supplement, vol. 32, no. 72, pp. 7–9, 2005. View at Google Scholar · View at Scopus
  3. S.-F. Li, “Levels and significance of TNF-α in peripheral blood and synovial fluid form patients with rheumatoid arthritis,” European Journal of Medical Research, vol. 16, no. 1, pp. 59–60, 2007. View at Google Scholar
  4. K. P. Redich, S. Hayen, and R. Ricct, “Ostecolasts are essential for INF-mediated joint destruction,” Arthritis Research, vol. 4, pp. 45–47, 2002. View at Google Scholar
  5. B.-S. Ouyang, J. Gao, J.-L. Che et al., “Effect of electro-acupuncture on tumor necrosis factor-α and vascular endothelial growth factor in peripheral blood and joint synovia of patients with rheumatoid arthritis,” Chinese Journal of Integrative Medicine, vol. 17, no. 7, pp. 505–509, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. B.-S. Ouyang, J.-L. Che, J. Gao et al., “Effects of electroacupuncture and simple acupuncture on changes of IL-1, IL-4, IL-6 and IL-10 in peripheral blood and joint fluid in patients with rheumatoid arthritis,” Zhongguo Zhen Jiu, vol. 30, no. 10, pp. 840–844, 2010. View at Google Scholar · View at Scopus
  7. G.-Y. Liu, X.-P. Li, T.-S. Ye et al., “Effect of acupuncture anti-inflammatory effects on adenosine receptor antagonist-caffeine in CIA rats,” Chinese Archives of Traditional Chinese Medicine, vol. 4, p. 77, 2012. View at Google Scholar
  8. J.-Q. Fang, X.-M. Shao, and G.-Z. Ma, “Effect of electroacupuncture at ‘Zusanli’ (ST 36) and ‘Sanyinjiao’ (SP 6) on collagen-induced arthritis and secretory function of knee-joint synoviocytes in rats,” Acupuncture Research, vol. 34, no. 2, pp. 93–96, 2009. View at Google Scholar
  9. L. Ottonello, M. Cutolo, G. Frumento et al., “Synovial fluid from patients with rheumatoid arthritis inhibits neutrophil apoptosis: role of adenosine and proinflammatory cytokines,” Rheumatology, vol. 41, no. 11, pp. 1249–1260, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. N. Goldman, M. Chen, T. Fujita et al., “Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture,” Nature Neuroscience, vol. 13, no. 7, pp. 883–888, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. Y.-K. Yim, H. Lee, K.-E. Hong et al., “Electro-acupuncture at acupoint ST36 reduces inflammation and regulates immune activity in collagen-induced arthritic mice,” Evidence-Based Complementary and Alternative Medicine, vol. 4, no. 1, pp. 51–57, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. Q.-H. Li, W.-X. Xie, X.-P. Li et al., “Adenosine A2A receptors mediate anti-inflammatory effects of electroacupuncture on synovitis in mice with collagen-induced arthritis,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, Article ID 809560, 11 pages, 2015. View at Publisher · View at Google Scholar
  13. G. Haskó and B. N. Cronstein, “Adenosine: an endogenous regulator of innate immunity,” Trends in Immunology, vol. 25, no. 1, pp. 33–39, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. L. Deng, Y. Gan, S. He et al., Chinese Acupuncture and Moxibustion, Foreign Languages Press, Beijing, China, 1997.
  15. P. A. Beavis, J. Stagg, P. K. Darcy, and M. J. Smyth, “CD73: a potent suppressor of antitumor immune responses,” Trends in Immunology, vol. 33, no. 5, pp. 231–237, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. L. Oliveira, A. Correia, A. Cristina Costa et al., “Deficits in endogenous adenosine formation by Ecto-5′-nucleotidase/CD73 impair neuromuscular transmission and immune competence in experimental autoimmune myasthenia gravis,” Mediators of Inflammation, vol. 2015, Article ID 460610, 16 pages, 2015. View at Publisher · View at Google Scholar
  17. P. Chrobak, R. Charlebois, P. Rejtar, R. El Bikai, B. Allard, and J. Stagg, “CD73 plays a protective role in collagen-induced arthritis,” The Journal of Immunology, vol. 194, no. 6, pp. 2487–2492, 2015. View at Publisher · View at Google Scholar
  18. C. Szabo and P. Pacher, “The outsiders: emerging roles of ectonucleotidases in inflammation,” Science Translational Medicine, vol. 4, no. 146, p. 146, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. V. Savic, V. Stefanovic, N. Ardaillou, and R. Ardaillou, “Induction of ecto-5′-nucleotidase of rat cultured mesangial cells by interleukin-1β and tumour necrosis factor-α,” Immunology, vol. 70, no. 3, pp. 321–326, 1990. View at Google Scholar · View at Scopus
  20. E. S. L. Chan, P. Fernandez, and B. N. Cronstein, “Adenosine in inflammatory joint diseases,” Purinergic Signalling, vol. 3, no. 1-2, pp. 145–152, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. S. Hitoglou, M. Hatzistilianou, D. Gougoustamou, F. Athanassiadou, A. Kotsis, and D. Catriu, “Adenosine deaminase activity and its isoenzyme pattern in patients with juvenile rheumatoid arthritis and systemic lupus erythematosus,” Clinical Rheumatology, vol. 20, no. 6, pp. 411–416, 2001. View at Publisher · View at Google Scholar · View at Scopus
  22. Z. Zakeri, S. Izadi, A. Niazi et al., “Comparison of adenosine deaminase levels in serum and synovial fluid between patients with rheumatoid arthritis and osteoarthritis,” International Journal of Clinical and Experimental Medicine, vol. 5, no. 2, pp. 195–200, 2012. View at Google Scholar
  23. H.-F. Wang, H.-L. Xia, J.-L. Qin et al., “The role of adenosine deaminase in the electroacupuncture preconditioning induced rapid tolerance to focal cerebral ischemia,” Chinese Journal of Integrative Medicine, vol. 33, no. 2, pp. 235–239, 2013. View at Google Scholar
  24. M. J. Zylka, “Needling adenosine receptors for pain relief,” Nature Neuroscience, vol. 13, no. 7, pp. 783–784, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. B. N. Cronstein, “Molecular therapeutics: methotrexate and its mechanism of action,” Arthritis and Rheumatism, vol. 39, no. 12, pp. 1951–1960, 1996. View at Publisher · View at Google Scholar · View at Scopus
  26. A. E. van Ede, R. F. J. M. Laan, R. A. De Abreu, A. B. J. Stegeman, and L. B. A. van de Putte, “Purine enzymes in patients with rheumatoid arthritis treated with methotrexate,” Annals of the Rheumatic Diseases, vol. 61, no. 12, pp. 1060–1064, 2002. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Salesi, R. A. Ghazvini, Z. Farajzadegan et al., “Serum adenosine deaminase in patients with rheumatoid arthritis treated with methotrexate,” Journal of Research in Pharmacy Practice, vol. 1, no. 2, pp. 72–76, 2012. View at Publisher · View at Google Scholar