Glucotoxicity Induced Oxidative Stress and Inflammation In Vivo and In Vitro in Psammomys obesus: Involvement of Aqueous Extract of Brassica rapa rapifera

Figure 2

Estimation of the viability, the apoptosis, the rate of proliferation, the cytochrome c, and ERK1/2 of vascular smooth muscle cells (VSMCs) of Psammomys obesus submitted to glucotoxicity (Glc 0.6% for 48 hours). Effect of aqueous extract of Brassica rapa (AEBr) at 2100 μg/mL for 24 hours. Data are expressed as mean ± standard deviation (S.D); (). Po: Psammomys obesus; Glc: D-Glucose. denotes a statistical difference; statistically different. (Po control + AEBr versus Po control); (Po VSMCs Glc + AEBr versus Po control + AEBr), (Po VSMCs Glc + AEBr versus Po control + AEBr), (Po VSMCs GLC versus Po VSMCs control) and (Po VSMCs Glc + AEBr versus Po VSMCs Glc).