Research Article

Glucotoxicity Induced Oxidative Stress and Inflammation In Vivo and In Vitro in Psammomys obesus: Involvement of Aqueous Extract of Brassica rapa rapifera

Table 4

Changes of inflammatory markers in adipose tissue in Psammomys obesus submitted to hyperglucidic diet (30% sucrose for 9 months). Effect of aqueous extract of Brassica rapa (AEBr) at 100 mg/kg for 20 consecutive days.

Inflammatory markersControlHGDControl + AEBrHGD + AEBr

NF-B P35 (pg/100 mg of organs)334 ± 13 587 ± 33323 ± 3 408 ± 21
TNFalpha (pg/100 mg of organs)34.98 ± 1.8134,2 ± 1031.38 ± 13.146.6 ± 13.8
MCP1 (pg/100 mg of organs)98.47 ± 6274 ± 4188.47 ± 5102 ± 12

Data are expressed as mean ± standard deviation (SD); (). Po: Psammomys obesus, HGD: hyperglucidic diet, and HGD + AEBr: hyperglucidic diet treated with aqueous extract of Brassica rapa. denotes a statistical difference; statistically different.
(Po control + AEBr versus Po control); (Po HGD versus Po control); (Po HGD versus Po control); (Po HGD + AEBr versus Po HGD); (Po HGD + AEBr versus Po HGD).