Glucotoxicity Induced Oxidative Stress and Inflammation In Vivo and In Vitro in Psammomys obesus: Involvement of Aqueous Extract of Brassica rapa rapifera

Table 5

Evaluation of inflammatory markers in vascular smooth muscle’s cells (VSMCs) of Psammomys obesus submitted to glucotoxicity (Glc 0.6% for 48 hours) and treated with aqueous extract of Brassica rapa (AEBr) at 2100 g/mL for 24 hours.

Inflammation markers	Control	Glc	Control + AEBr	Glc + AEBr
NO (pmol/10^6 cells)	16.28 ± 1.31	30.73 ± 3.62	23.71 ± 1.55	11.51 ± 3.48
TNFα (pg/10^6 cells)	14.46 ± 0.95	172.85 ± 9.32	17.20 ± 0.86	119.31 ± 4.25
MCP1 (pg/10^6 cells)	30.85 ± 4.68	164.48 ± 2.34	49.27 ± 10.17	80 ± 8.56
NF-B P35 (pg/10^6 cells)	17.86 ± 1.10	72.69 ± 2.72	16.58 ± 1.13	33.08 ± 0.59

Data are expressed as mean ± standard deviation (SD); (). Po: Psammomys obesus and GLC: D-Glucose. denotes a statistical difference; statistically different.
(Po VSMCs control + AEBr versus Po VSMCs control); (Po VSMCs Glc versus Po VSMCs control); (Po VSMCs Glc + AEBr versus Po control + AEBr); (Po VSMCs Glc + AEBr versus Po VSMCs Glc).