Glucotoxicity Induced Oxidative Stress and Inflammation In Vivo and In Vitro in Psammomys obesus: Involvement of Aqueous Extract of Brassica rapa rapifera

Table 6

Evaluation of redox states in vascular smooth muscle’s cells (VSMCs) of Psammomys obesus submitted to glucotoxicity (Glc 0.6% for 48 hours) and treated with aqueous extract of Brassica rapa (AEBr) at 2100 g/mL for 24 hours.

Redox states	Control	Glc	Control + AEBr	Glc + AEBr
Catalase (UI/min^−1 mg^−1 protein ×10^6 cells)	0.102 ± 0.005	0.031 ± 0.012	0.067 ± 0.029	0.158 ± 0.008
SOD (UI/mg^−1 protein ×10^6 cells)	1.38 ± 0	0.68 ± 0.01	1.14 ± 0	2.07 ± 0.16
TBARs CIC (µmol/10^6 cells)	1.08 ± 0.05	1.71 ± 0.15	0.49 ± 0.13	0.39 ± 0.05
TBARs CEC (µmol/10^6 cells)	0.85 ± 0.01	2.32 ± 0.02	1.13 ± 0.034	0.91 ± 0.02
protein carbonyls (pmol/10^6 cells)	0.77 ± 0.21	10.52 ± 0.23	0.76 ± 0.11	2.48 ± 0.12
AOPP (pmol/10^6 cells)	216.09 ± 10.8	349.67 ± 37.05	209.65 ± 35.6	93.72 ± 9.11

Data are expressed as mean ± standard deviation (SD); (). Po: Psammomys obesus, Glc: D-Glucose, SOD: superoxide dismutase, and AOPP: advanced protein oxidation products. denotes a statistical difference; statistically different.
(Po control + AEBr versus Po control); (Po VSMCs Glc + AEBr versus Po control + AEBr); (Po VSMCs Glc versus Po VSMCs control); (Po VSMCs Glc + AEBr versus Po control + AEBr); (Po VSMCs Glc + AEBr versus Po VSMCs Glc).