Analgesic and Antipyretic Activities of Methanol Extract and Its Fraction from the Root of Schoenoplectus grossus
Table 2
Antipyretic effect of methanol extract from root of S. grossus and its fraction in yeast induced pyrexia in rats.
Treatment
Dose (mg/kg)
Basal temp. °F
Rectal temperature (°F)
0 hour (after 18 hr)
1 hr
2 hr
3 hr
4 hr
Control
99.0
100.6 ± 0.300
100.7 ± 0.277
100.7 ± 0.187
100.68 ± 0.191
100.66 ± 0.194
Paracetamol
100
98.56
100.56 ± 0.326
99.82 ± 0.124
99.2 ± 0.192
98.86 ± 0.051
98.32 ± 0.097
Methanol
400
98.42
99.68 ± 0.193
99.54 ± 0.229
99.06 ± 0.266
98.70 ± 0.210
98.3 ± 0.214
Methanol
200
98.52
99.76 ± 0.229
99.5 ± 0.207
98.9 ± 0.217
98.88 ± 0.206
98.26 ± 0.378
Petroleum ether
400
98.54
99.88 ± 0.097
99.56 ± 0.117
99.28 ± 0.116
98.92 ± 0.193
98.34 ± 0.189
Petroleum ether
200
98.48
99.82 ± 0.169
99.62 ± 0.188
99.04 ± 0.250
98.7 ± 0.263
98.40 ± 0.230
Values are represented in mean ± SEM (). MANNOVA followed by Dunnett’s multiple comparisons was performed to analyze this dataset. was considered significant compared to control; , , and .