Research Article

Analgesic and Antipyretic Activities of Methanol Extract and Its Fraction from the Root of Schoenoplectus grossus

Table 2

Antipyretic effect of methanol extract from root of S. grossus and its fraction in yeast induced pyrexia in rats.

TreatmentDose (mg/kg)Basal temp. °F Rectal temperature (°F)
0 hour (after 18 hr)1 hr2 hr3 hr4 hr

Control99.0 100.6 ± 0.300100.7 ± 0.277100.7 ± 0.187100.68 ± 0.191100.66 ± 0.194
Paracetamol10098.56 100.56 ± 0.32699.82 ± 0.12499.2 ± 0.19298.86 ± 0.05198.32 ± 0.097
Methanol 400 98.4299.68 ± 0.19399.54 ± 0.22999.06 ± 0.26698.70 ± 0.21098.3 ± 0.214
Methanol 200 98.5299.76 ± 0.22999.5 ± 0.20798.9 ± 0.21798.88 ± 0.20698.26 ± 0.378
Petroleum ether 400 98.5499.88 ± 0.09799.56 ± 0.11799.28 ± 0.11698.92 ± 0.19398.34 ± 0.189
Petroleum ether 200 98.4899.82 ± 0.16999.62 ± 0.18899.04 ± 0.25098.7 ± 0.26398.40 ± 0.230

Values are represented in mean ± SEM (). MANNOVA followed by Dunnett’s multiple comparisons was performed to analyze this dataset. was considered significant compared to control; , , and .