Evaluation of Hypoglycemic and Genotoxic Effect of Polyphenolic Bark Extract from Quercus sideroxyla

Table 3

DNA damage according to the comet assay for the assessment of the genotoxicity of polyphenolic extract from Q. sideroxyla bark.

Treatment		Comet class
	Total	0	1	2	3
Blood sample (4 h)
Negative control
CPA (50 mg/kg)
CE100
CE200
Blood sample (24 h)
Negative control
CPA (50 mg/kg)
CE100
CE200

Each value represents the mean of observations ± standard deviation. a: significant difference versus negative control group, b: versus CPA 50 mg/kg, and c: versus CE100; () LSD, comparing the treatments separately at 4 and 24 hours.
CPA: group treated with cyclophosphamide; CE100: group treated with crude extract at dose of 100 mg/kg; CE200: group treated with crude extract at dose of 200 mg/kg.