Research Article

Prevention and Therapeutic Effects and Mechanisms of Tanshinone IIA Sodium Sulfonate on Acute Liver Injury Mice Model

Figure 2

TSS improves liver histological alterations in mice with D-Gal-induced ALI. Morphological changes in liver tissues were observed through liver section hematoxylin-eosin staining. (a) Mice treated with physiological saline; (b) mice exposed to D-Gal (450 mg⋅kg−1); (c) mice pretreated with TSS (100 mg⋅kg−1) before D-Gal exposure; (d) mice treated with TSS (100 mg⋅kg−1) alone after D-Gal exposure; (e) mice treated with TSS (100 mg⋅kg−1) and MI (45 mg⋅kg−1) after D-Gal exposure. Representative liver sections of each group are shown (original magnification: 400x).
(a)
(b)
(c)
(d)
(e)