Identification of Plants That Inhibit Lipid Droplet Formation in Liver Cells: Rubus suavissimus Leaf Extract Protects Mice from High-Fat Diet-Induced Fatty Liver by Directly Affecting Liver Cells

Figure 1

Inhibitory effects of plant extracts (5%) on lipid droplet formation in Hepa 1–6 cells treated with oleic acid. Dried plants were ground with a mill and 0.05 g of the resulting powder was extracted with 500 μL of water at 60°C for 1 h. (a) No plant extract, (b) water extract of Ginkgo leaves (Ginkgo biloba L.), (c) water extract of Hibiscus flower (Hibiscus sabdariffa L.), and (d) water extract of Platycodon root (Platycodon grandiflorum A.). Details are described in Section 2.

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(b)

(c)

(d)