Effect of Loquat Leaf Extract on Muscle Strength, Muscle Mass, and Muscle Function in Healthy Adults: A Randomized, Double-Blinded, and Placebo-Controlled Trial
Table 4
Comparison of the metabolic parameters between the two groups.
Variables
LLE group ()
Placebo group ()
P
Week 0
Week 12
Δ12-0 weeks
P
Week 0
Week 12
Δ12-0 weeks
P
Pyruvate
0.85 0.41
0.75 0.49
−0.11 0.53
0.307
0.87 0.4
0.85 0.31
−0.02 0.38
0.773
0.499
Lactate
1.32 0.89
1.02 0.54
−0.3 0.86
0.085
1.41 0.93
1.31 0.77
−0.11 0.84
0.514
0.419
Creatinine
0.71 0.12
0.66 0.14
−0.06 0.11
0.017
0.74 0.18
0.69 0.17
−0.06 0.11
0.014
0.990
AST
23.2 4.9
19.8 4.4
−3.4 4.3
<0.001
23.6 4.4
20.6 4.0
−3.1 3.5
<0.001
0.783
ALT
13.3 4.0
12.5 4.5
−0.7 3.0
0.210
15.5 6.5
13.8 5.1
−1.7 5.3
0.116
0.435
GGT
15.4 7.5
14.3 6.7
−1.2 3.2
0.061
20.3 13.1
18.8 15.2
−1.4 5.0
0.149
0.822
Glucose
89 6.5
91.8 10.0
2.8 8.9
0.113
91.7 9.4
95.0 10.5
3.3 8.1
0.044
0.836
Insulin
4.4 1.5
4.9 2.3
0.5 1.8
0.166
5.4 2.6
5.7 3.3
0.4 3.2
0.561
0.872
CK
88.2 42.4
77.4 29.6
−10.8 40.0
0.173
125.1 195.2
116 137.6
−9.1 68.1
0.493
0.913
Na
140.1 1.5
139.0 2.2
−1.1 2.6
0.045
140.2 1.6
139.4 2.0
−0.8 1.9
0.038
0.635
K
4.3 0.3
4.2 0.3
−0.1 0.4
0.201
4.4 0.3
4.3 0.2
−0.1 0.3
0.051
0.862
Cl
104.6 1.8
103.6 1.6
−0.9 2.0
0.022
104.6 1.8
104.3 2.3
−0.4 1.7
0.272
0.275
HDL
61.3 12.5
60.3 12.6
−1 8.8
0.558
58.9 13.1
58.4 15.0
−0.5 9.7
0.784
0.849
LDL
101.1 25.5
144.3 119.2
43.1 122.3
0.084
100.9 23.1
112.9 28.7
12 21.4
0.007
0.199
Triglyceride
80.7 50.8
78.6 35.3
−2.07 31.7
0.736
85.1 46.0
77.7 36.4
−7.4 30.1
0.210
0.526
LLE: loquat leaf extract; AST: aspartate aminotransferase; ALT: alanine aminotransferase; GGT: γ-glutamyl transferase; CK: creatinine kinase; HDL: high-density lipoprotein; LDL: low-density lipoprotein. Data are expressed as mean SD. Paired -test for within-group. Two-sample test between groups for comparison of the difference from baseline.
