Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2016, Article ID 4541580, 10 pages
http://dx.doi.org/10.1155/2016/4541580
Research Article

Decoction and Fermentation of Selected Medicinal Herbs Promote Hair Regrowth by Inducing Hair Follicle Growth in Conjunction with Wnts Signaling

1College of Life Science, Gangneung-Wonju National University, 120 Gangneung Daehangno, Gangneung, Gangwon 210-702, Republic of Korea
2College of Pharmacy, Chung-Ang University, 221 Heukseok-dong, Dongjak-gu, Seoul 156-756, Republic of Korea
3Industry-Academic Cooperation Foundation, Hanbat National University, Daejeon 305-719, Republic of Korea
4Heo-jong Oriental Medicine Clinic, Mia-dong, Gangbuk-gu 62-3, Seoul 01205, Republic of Korea

Received 26 November 2015; Revised 25 January 2016; Accepted 7 February 2016

Academic Editor: Jian-Li Gao

Copyright © 2016 Su Kil Jang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Paus and G. Cotsarelis, “The biology of hair follicles,” The New England Journal of Medicine, vol. 341, no. 7, pp. 491–497, 1999. View at Publisher · View at Google Scholar · View at Scopus
  2. E. Fuchs, B. J. Merrill, C. Jamora, and R. Dasgupta, “At the roots of a never-ending cycle,” Developmental Cell, vol. 1, no. 1, pp. 13–25, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Claudinot, M. Nicolas, H. Oshima, A. Rochat, and Y. Barrandon, “Long-term renewal of hair follicles from clonogenic multipotent stem cells,” Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 41, pp. 14677–14682, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Ohyama, A. Terunuma, C. L. Tock et al., “Characterization and isolation of stem cell-enriched human hair follicle bulge cells,” The Journal of Clinical Investigation, vol. 116, no. 1, pp. 249–260, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. W. E. Lowry, C. Blanpain, J. A. Nowak, G. Guasch, L. Lewis, and E. Fuchs, “Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells,” Genes & Development, vol. 19, no. 13, pp. 1596–1611, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Reddy, T. Andl, A. Bagasra et al., “Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis,” Mechanisms of Development, vol. 107, no. 1-2, pp. 69–82, 2001. View at Publisher · View at Google Scholar · View at Scopus
  7. V. Greco, T. Chen, M. Rendl et al., “A two-step mechanism for stem cell activation during hair regeneration,” Cell Stem Cell, vol. 4, no. 2, pp. 155–169, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. J. C. Ra, I. S. Shin, S. H. Kim et al., “Safety of intravenous infusion of human adipose tissue-derived mesenchymal stem cells in animals and humans,” Stem Cells and Development, vol. 20, no. 8, pp. 1297–1308, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. D. Park, G. Yang, D. K. Bae et al., “Human adipose tissue-derived mesenchymal stem cells improve cognitive function and physical activity in ageing mice,” Journal of Neuroscience Research, vol. 91, no. 5, pp. 660–670, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Müller-Röver, B. Handjiski, C. van der Veen et al., “A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages,” The Journal of Investigative Dermatology, vol. 117, no. 1, pp. 3–15, 2001. View at Publisher · View at Google Scholar · View at Scopus
  11. T. Andl, S. T. Reddy, T. Gaddapara, and S. E. Millar, “WNT signals are required for the initiation of hair follicle development,” Developmental Cell, vol. 2, no. 5, pp. 643–653, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. D. M. Danilenko, B. D. Ring, D. Yanagihara et al., “Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation: normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia,” American Journal of Pathology, vol. 147, no. 1, pp. 145–154, 1995. View at Google Scholar · View at Scopus
  13. G. S. Kim, D. H. Kim, J. J. Lim et al., “Biological and antibacterial activities of the natural herb Houttuynia cordata water extract against the intracellular bacterial pathogen Salmonella within the RAW 264.7 macrophage,” Biological & Pharmaceutical Bulletin, vol. 31, no. 11, pp. 2012–2017, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. X.-Y. Yang, G.-S. Park, M. H. Lee et al., “Toll-like receptor 4-mediated immunoregulation by the aqueous extract of Mori Fructus,” Phytotherapy Research, vol. 23, no. 12, pp. 1713–1720, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. H.-S. Lee, J.-H. Choi, Y.-E. Kim, I.-H. Kim, B.-M. Kim, and C.-H. Lee, “Effects of the cynanchum wilfordii ethanol extract on the serum lipid profile in hypercholesterolemic rats,” Preventive Nutrition and Food Science, vol. 18, no. 3, pp. 157–162, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. X.-Y. Wang, Z.-L. Yu, S.-Y. Pan et al., “Supplementation with the extract of schisandrae fructus pulp, seed, or their combination influences the metabolism of lipids and glucose in mice fed with normal and hypercholesterolemic diet,” Evidence-Based Complementary and Alternative Medicine, vol. 2014, Article ID 472638, 11 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  17. Y. Shi, J. Dong, J. Zhao, L. Tang, and J. Zhang, “Herbal insomnia medications that target GABAergic systems: a review of the psychopharmacological evidence,” Current Neuropharmacology, vol. 12, no. 3, pp. 289–302, 2014. View at Publisher · View at Google Scholar
  18. Z. Pang, Z. Zhi-Yan, W. Wang et al., “The advances in research on the pharmacological effects of Fructus Ligustri Lucidi,” BioMed Research International, vol. 2015, Article ID 281873, 5 pages, 2015. View at Publisher · View at Google Scholar
  19. L. Alonso and E. Fuchs, “Stem cells in the skin: waste not, Wnt not,” Genes & Development, vol. 17, no. 10, pp. 1189–1200, 2003. View at Publisher · View at Google Scholar · View at Scopus
  20. J. Fu and W. Hsu, “Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis,” Journal of Investigative Dermatology, vol. 133, no. 4, pp. 890–898, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. Y. Zhang, P. Tomann, T. Andl et al., “Reciprocal requirements for EDA/EDAR/NF-κB and Wnt/β-catenin signaling pathways in hair follicle induction,” Developmental Cell, vol. 17, no. 1, pp. 49–61, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. S. E. Millar, K. Willert, P. C. Salinas et al., “WNT signaling in the control of hair growth and structure,” Developmental Biology, vol. 207, no. 1, pp. 133–149, 1999. View at Publisher · View at Google Scholar · View at Scopus
  23. A. E. Oro and K. Higgins, “Hair cycle regulation of Hedgehog signal reception,” Developmental Biology, vol. 255, no. 2, pp. 238–248, 2003. View at Publisher · View at Google Scholar · View at Scopus
  24. C. van Genderen, R. M. Okamura, I. Farinas et al., “Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice,” Genes & Development, vol. 8, no. 22, pp. 2691–2703, 1994. View at Publisher · View at Google Scholar · View at Scopus
  25. P. Zhou, C. Byrne, J. Jacobs, and E. Fuchs, “Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate,” Genes & Development, vol. 9, no. 6, pp. 700–713, 1995. View at Publisher · View at Google Scholar · View at Scopus
  26. R. DasGupta and E. Fuchs, “Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation,” Development, vol. 126, no. 20, pp. 4557–4568, 1999. View at Google Scholar · View at Scopus
  27. B. A. Bunnell, M. Flaat, C. Gagliardi, B. Patel, and C. Ripoll, “Adipose-derived stem cells: isolation, expansion and differentiation,” Methods, vol. 45, no. 2, pp. 115–120, 2008. View at Publisher · View at Google Scholar · View at Scopus