Evaluation of Hepatoprotective Activity of Adansonia digitata Extract on Acetaminophen-Induced Hepatotoxicity in Rats

Figure 5

Histopathological study of liver tissue in control, acetaminophen, silymarin, and Adansonia digitata extract groups of rats. (a) Control group showed normal liver architecture (H&E ×40). (b) Acetaminophen group showed marked hepatic cell necrosis and moderate inflammation and lymphocytic infiltrations (H&E ×40). (c) Acetaminophen + Silymarin (100 mg/kg) showed nearly normal liver structure (H&E ×100). (d) Acetaminophen + Adansonia digitata extract (200 mg/kg) showed mild necrosis and inflammation (H&E ×100).

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