Research Article
Evaluation of Toxicological Effects of an Aqueous Extract of Shells from the Pecan Nut Carya illinoinensis (Wangenh.) K. Koch and the Possible Association with Its Inorganic Constituents and Major Phenolic Compounds
Table 3
Evaluation of the genotoxic activity of ellagic acid (EA) and gallic acid (GA) using comet assay in blood tissue of mice.
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NaCl 0.9% + DMSO 5% (dimethyl sulfoxide). Hydrogen peroxide 0.25 mM (ex vivo treatment: slides from vehicle group treated for 5 min with H2O2 0.25 mM). DI: damage index, from zero (no damage, 0 × 100 cells) to 400 (with maximum damage, 4 × 100). DF: damage frequency, calculated based on the number of cells with damage versus those without damage. : significant difference in comparison with the vehicle group (ANOVA, Dunnett’s test). |