Antioxidant and Wound Healing Activity of Polyherbal Fractions of Clinacanthus nutans and Elephantopus scaber
Table 4
Mean area of wound (mm2) and % wound contraction during burn wound model.
Days
Day 0 (before treatment)
3
6
9
12
15
17
19
Group 1 (ethyl acetate)
499 ± 3.53 (0.00)
291.75 ± 3.44 (41.53)
264.5 ± 4.66 (46.99)
256.5 ± 2.84 (48.59)
60.5 ± 3.79 (87.87)
25.5 ± 2.53 (94.88)
0.00 ± 0.00 (0.00)
0.00 ± 0.00 (0.00)
Group 2 (n-butanol)
476.75 ± 9.25 (0.00)
371.75 ± 6.57 (22.02)
265 ± 5.49 (44.41)
200.75 ± 8.17 (57.89)
138.75 ± 7.4 (70.89)
59.75 ± 3.14 (87.46)
0.00 ± 0.00 (0.00)
0.00 ± 0.00 (0.00)
Group 3 (aqueous)
489.75 ± 1.84 (0.00)
311.25 ± 1.10 (36.44)
177.25 ± 2.75 (63.80)
81.5 ± 1.55 (83.35)
48.5 ± 1.55 (90.09)
0.00 ± 0.00 (0.00)
0.00 ± 0.00 (0.00)
0.00 ± 0.00 (0.00)
Group 4 (standard)
492 ± 4.02 (0.00)
318.5 ± 5.51 (35.26)
317.5 ± 3.37 (35.46)
255.5 ± 4.34 (48.06)
114.5 ± 3.77 (76.72)
28.25 ± 2.65 (94.25)
0.00 ± 0.00 (0.00)
0.00 ± 0.00 (0.00)
Group 5 (control)
496.5 ± 5.60 (0.00)
424.25 ± 8.40 (14.55)
324 ± 7.42 (34.74)
323.5 ± 7.5 (34.84)
207.25 ± 5.92 (58.25)
119.5 ± 6.13 (75.93)
56.5 ± 5.75 (88.62)
26.75 ± 5.50 (94.61)
Values are mean ± SEM (percent) of 4 rats in each group. , , and compared to respective day control group (statistical analysis was done by one-way analysis of variance followed by Dunnett’s test for multiple comparisons).
