Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2016 (2016), Article ID 4723530, 9 pages
http://dx.doi.org/10.1155/2016/4723530
Research Article

Addition and Subtraction Theory of TCM Using Xiao-Chaihu-Decoction and Naturopathy in Predicting Survival Outcomes of Primary Liver Cancer Patients: A Prospective Cohort Study

Department of Traditional Chinese Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China

Received 31 May 2016; Revised 20 August 2016; Accepted 29 August 2016

Academic Editor: Kieran Cooley

Copyright © 2016 Min Dai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A.-L. Cheng, Z. Guan, Z. Chen et al., “Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: subset analyses of the phase III Sorafenib Asia-Pacific trial,” European Journal of Cancer, vol. 48, no. 10, pp. 1452–1465, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. P. Bertuccio, C. Bosetti, F. Levi, A. Decarli, E. Negri, and C. La Vecchia, “A comparison of trends in mortality from primary liver cancer and intrahepatic cholangiocarcinoma in Europe,” Annals of Oncology, vol. 24, no. 6, pp. 1667–1674, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. Y. Chen, X. Wang, J. Wang, Z. Yan, and J. Luo, “Excess body weight and the risk of primary liver cancer: an updated meta-analysis of prospective studies,” European Journal of Cancer, vol. 48, no. 14, pp. 2137–2145, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. Y.-M. Zhou, X.-F. Zhang, L.-P. Wu, C.-J. Sui, and J.-M. Yang, “Risk factors for combined hepatocellular-cholangiocarcinoma: a hospital-based case-control study,” World Journal of Gastroenterology, vol. 20, no. 35, pp. 12615–12620, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. T. Shimazu, S. Sasazuki, K. Wakai et al., “Alcohol drinking and primary liver cancer: a pooled analysis of four Japanese cohort studies,” International Journal of Cancer, vol. 130, no. 11, pp. 2645–2653, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. T. Lu, W.-K. Seto, R.-X. Zhu, C.-L. Lai, and M.-F. Yuen, “Prevention of hepatocellular carcinoma in chronic viral hepatitis B and C infection,” World Journal of Gastroenterology, vol. 19, no. 47, pp. 8887–8894, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. T. M. Welzel, B. I. Graubard, S. Zeuzem, H. B. El-Serag, J. A. Davila, and K. A. Mcglynn, “Metabolic syndrome increases the risk of primary liver cancer in the United States: a study in the SEER-medicare database,” Hepatology, vol. 54, no. 2, pp. 463–471, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. T. M. Welzel, B. I. Graubard, H. B. El-Serag et al., “Risk factors for intrahepatic and extrahepatic cholangiocarcinoma in the United States: a population-based case-control study,” Clinical Gastroenterology and Hepatology, vol. 5, no. 10, pp. 1221–1228, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. B. Blechacz and G. J. Gores, “Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment,” Hepatology, vol. 48, no. 1, pp. 308–321, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. W. S. Yang, X. O. Shu, J. Gao et al., “Prospective evaluation of type 2 diabetes mellitus on the risk of primary liver cancer in chinese men and women,” Annals of Oncology, vol. 24, no. 6, pp. 1679–1685, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. Zhou, C. Sui, B. Li et al., “Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review,” World Journal of Surgical Oncology, vol. 8, article 55, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. K. H. Kim, S. G. Lee, E. H. Park et al., “Surgical treatments and prognoses of patients with combined hepatocellular carcinoma and cholangiocarcinoma,” Annals of Surgical Oncology, vol. 16, no. 3, pp. 623–629, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Goel and K. Sharma, “Plant extracts and phytochemicals as herbal medicines and antimicrobials,” International Journal of Biological and Medical Research, vol. 5, pp. 3940–3946, 2014. View at Google Scholar
  14. A. Flower, L.-Q. Wang, G. Lewith, J. P. I. Liu, and Q. Li, “Chinese herbal medicine for treating recurrent urinary tract infections in women,” The Cochrane Database of Systematic Reviews, no. 6, Article ID CD010446, 2015. View at Publisher · View at Google Scholar · View at Scopus
  15. X. Xiong, X. Yang, Y. Liu, Y. Zhang, P. Wang, and J. Wang, “Chinese herbal formulas for treating hypertension in traditional Chinese medicine: perspective of modern science,” Hypertension Research, vol. 36, no. 7, pp. 570–579, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. F. H. Qi, Z. X. Wang, P. P. Cai et al., “Traditional Chinese medicine and related active compounds: a review of their role on hepatitis B virus infection,” Drug Discoveries and Therapeutics, vol. 7, no. 6, pp. 212–224, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. X. Li, X. Xu, J. Wang et al., “A system-level investigation into the mechanisms of Chinese Traditional Medicine: compound danshen formula for cardiovascular disease treatment,” PLoS ONE, vol. 7, no. 9, Article ID e43918, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. S. Li and B. Zhang, “Traditional Chinese medicine network pharmacology: theory, methodology and application,” Chinese Journal of Natural Medicines, vol. 11, no. 2, pp. 110–120, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Li, C. Qiao, L. Qin, J. Zhang, and C. Ling, “Application of Traditional Chinese Medicine injection in treatment of primary liver cancer: a review,” Journal of Traditional Chinese Medicine, vol. 32, no. 3, pp. 299–307, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. D. Su and L. Li, “Trends in the use of complementary and alternative medicine in the United States: 2002–2007,” Journal of Health Care for the Poor and Underserved, vol. 22, no. 1, pp. 296–310, 2011. View at Google Scholar · View at Scopus
  21. J. Wardle, C.-W. Lui, and J. Adams, “Complementary and alternative medicine in rural communities: current research and future directions,” Journal of Rural Health, vol. 28, no. 1, pp. 101–112, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. T. Ishii, Y. Goto, H. Matsuzaki et al., “Pulmonary metastasis of combined hepatocellular and cholangiocarcinoma: a unique radiographic presentation with air-space consolidation masquerading as pneumonia and primary pulmonary adenocarcinoma,” Internal Medicine, vol. 54, no. 11, pp. 1389–1392, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. C. H. Cheng, C. F. Lee, T. H. Wu et al., “Evaluation of the new AJCC staging system for resectable hepatocellular carcinoma,” World Journal of Surgical Oncology, vol. 9, no. 1, p. 114, 2011. View at Publisher · View at Google Scholar
  24. J. E. Kim, J. Y. Lee, Y. J. Kim et al., “Acoustic radiation force impulse elastography for chronic liver disease: comparison with ultrasound-based scores of experienced radiologists, child-pugh scores and liver function tests,” Ultrasound in Medicine and Biology, vol. 36, no. 10, pp. 1637–1643, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. E. A. Eisenhauer, P. Therasse, J. Bogaerts et al., “New response evaluation criteria in solid TUMORs: revised RECIST guideline (version 1.1),” European Journal of Cancer, vol. 45, no. 2, pp. 228–247, 2009. View at Publisher · View at Google Scholar
  26. A. Jemal, F. Bray, M. M. Center, J. Ferlay, E. Ward, and D. Forman, “Global cancer statistics,” CA: A Cancer Journal for Clinicians, vol. 61, no. 2, pp. 69–90, 2011. View at Publisher · View at Google Scholar
  27. X.-J. Xiong, F.-Y. Chu, H.-X. Li, and Q.-Y. He, “Clinical application of the TCM classic formulae for treating chronic bronchitis,” Journal of Traditional Chinese Medicine, vol. 31, no. 1, pp. 69–72, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Zhou and C. Zhou, “Exploration on the effect of xiaochaihu decoction treatment of breast cancer,” Journal of the Chinese Medical, no. 2, pp. 163–165, 2015. View at Google Scholar
  29. M. X. Qi, H. L. Ning, Y. F. Yang, L. Y. Lv, and J. B. He, “Study on the effect of Xiaochaihu decoction on Type 2 diabetic mice,” HerMed, vol. 33, no. 4, pp. 434–438, 2014. View at Google Scholar
  30. X. H. Feng and Z. X. Rao, “The effect of Wulingsan combined with Xiaochaihu Decoction combined with Valsartan capsules treatment of chronic glomerulonephritis,” China Continuing Medical Education, vol. 7, no. 27, pp. 212–213, 2015. View at Google Scholar
  31. N. Zheng, J. Dai, H. Cao et al., “Current understanding on antihepatocarcinoma effects of Xiao Chai Hu Tang and its constituents,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 529458, 14 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  32. C.-S. Zheng, Y.-S. Wu, H.-J. Bao et al., “Understanding the polypharmacological anticancer effects of Xiao Chai Hu tang via a computational pharmacological model,” Experimental and Therapeutic Medicine, vol. 7, no. 6, pp. 1777–1783, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. X.-Q. Liu, X.-J. Hu, H.-X. Xu, and X.-Y. Zeng, “Xiaochaihu Decoction attenuates the vicious circle between the oxidative stress and the ALP inactivation through LPS-catecholamines interactions in gut, liver and brain during CCI4+ethanol-induced mouse HCC,” BMC Complementary and Alternative Medicine, vol. 13, article 375, 2013. View at Publisher · View at Google Scholar · View at Scopus
  34. X. W. Zhang, P. H. Chen, X. Y. Jin et al., “Comparative study of pharmacodynamics between ultrafine powder and traditional processing of Xiaochaihu Decoction,” Chinese Traditional Patent Medicine, vol. 2, p. 010, 2011. View at Google Scholar
  35. M.-Y. Sun, L. Wang, Y.-P. Mu et al., “Effects of Chinese herbal medicine Yinchenhao Decoction on expressions of apoptosis-related genes in dimethylnitrosamine- or carbon tetrachloride-induced liver cirrhosis in rats,” Journal of Chinese Integrative Medicine, vol. 9, no. 4, pp. 423–434, 2011. View at Publisher · View at Google Scholar · View at Scopus
  36. A. P. Venook, C. Papandreou, J. Furuse, and L. L. de Guevara, “The incidence and epidemiology of hepatocellular carcinoma: a global and regional perspective,” The Oncologist, vol. 15, supplement 4, pp. 5–13, 2010. View at Google Scholar · View at Scopus
  37. S.-Y. Han and P.-P. Li, “Progress of research in antitumor mechanisms with Chinese medicine,” Chinese Journal of Integrative Medicine, vol. 15, no. 4, pp. 316–320, 2009. View at Publisher · View at Google Scholar · View at Scopus
  38. J. L. Wardle, J. Adams, C.-W. Lui, and A. E. Steel, “Current challenges and future directions for naturopathic medicine in Australia: a qualitative examination of perceptions and experiences from grassroots practice,” BMC Complementary and Alternative Medicine, vol. 13, article 15, 2013. View at Publisher · View at Google Scholar · View at Scopus
  39. Y. Niwa, H. Matsuura, M. Murakami, J. Sato, K. Hirai, and H. Sumi, “Evidence that naturopathic therapy including Cordyceps sinensis prolongs survival of patients with hepatocellular carcinoma,” Integrative Cancer Therapies, vol. 12, no. 1, pp. 50–68, 2013. View at Publisher · View at Google Scholar · View at Scopus
  40. D. P. Braun, D. Gupta, T. C. Birdsall, M. Sumner, and E. D. Staren, “Effect of naturopathic and nutritional supplement treatment on tumor response, control, and recurrence in patients with prostate cancer treated with radiation therapy,” Journal of Alternative and Complementary Medicine, vol. 19, no. 3, pp. 198–203, 2013. View at Publisher · View at Google Scholar · View at Scopus
  41. D. V. Arankalle, “Integrating naturopathy and yoga in management of musculoskeletal disorders,” International Journal of Preventive Medicine, vol. 4, no. 1, pp. 120–121, 2013. View at Google Scholar · View at Scopus
  42. J. Wardle and E. B. Oberg, “The intersecting paradigms of naturopathic medicine and public health: opportunities for naturopathic medicine,” Journal of Alternative and Complementary Medicine, vol. 17, no. 11, pp. 1079–1084, 2011. View at Publisher · View at Google Scholar · View at Scopus
  43. A. Steel and J. Adams, “The role of naturopathy in pregnancy, labour and post-natal care: broadening the evidence-base,” Complementary Therapies in Clinical Practice, vol. 17, no. 4, pp. 189–192, 2011. View at Publisher · View at Google Scholar · View at Scopus