Evidence-Based Complementary and Alternative Medicine

Research Article

Addition and Subtraction Theory of TCM Using Xiao-Chaihu-Decoction and Naturopathy in Predicting Survival Outcomes of Primary Liver Cancer Patients: A Prospective Cohort Study

Table 1

Baseline characteristics among groups.


Group	XCHD group ()	NM group ()	Combined group ()	P
Group	XCHD group ()	NM group ()	Combined group ()	(XCHD group versus NM group)	(XCHD group versus combined group)	(NM group versus combined group)

Age (year)	51.05 ± 13.63	50.10 ± 17.04	49.33 ± 12.41	0.697	0.428	0.751
Gender (female/male)	61/15	76/13	58/12	0.382	0.687	0.663
KPS	65.21 ± 10.14	69.33 ± 11.47	87.67 ± 12.62	0.016	<0.001	<0.001
Body weight	58.05 ± 9.43	60.16 ± 8.98	59.73 ± 9.11	0.144	0.276	0.766
Smoking (yes/no)	64/12	70/19	59/11	0.362	0.990	0.367
AFP (≤400/>400, umol/L)	37/39	39/50	30/40	0.532	0.480	0.903
HbsAg (positive/negative)	69/7	81/8	64/6	0.961	0.892	0.927
TBIL (≤17.1/>17.1, umol/L)	58/18	69/20	49/21	0.854	0.389	0.281
Tumor diameter (cm)	8.50 ± 2.44	8.67 ± 2.02	8.58 ± 2.30	0.646	0.980	0.785
Tumor number (singly/multiply)	45/31	49/40	41/29	0.591	0.938	0.657

XCHD: Xiao-Chaihu-Decoction; NM: naturopathic medicine. XCHD group, application of the addition and subtraction theory of TCM using Xiao-Chaihu-Decoction; NM group, receiving naturopathic medicine therapy; combined group, Xiao-Chaihu-Decoction combined with naturopathic medicine therapy. KPS, Karnofsky performance score; AFP, alpha fetal protein; TBIL, total bilirubin. indicated a statistically significance, indexes without statistical difference between groups by χ² test also showed none apparent statistical difference among groups by the one-way analysis of variance (ANOVA) test.