The Induction of Apoptosis in A375 Malignant Melanoma Cells by Sutherlandia frutescens

Figure 2

The effect of S. frutescens on the morphology of A375 cells. Control-treated cells (a)–(c) are typical, healthy A375 cells which become more confluent with an increase in treatment time. S. frutescens extract causes morphological changes in the A375 cells (d)–(f). These include the loss of adherence and cell shrinkage. The scale bar represents 20 μm.

(a) Control (24 h)

(b) Control (48 h)

(c) Control (72 h)

(d) S. frutescens (24 h)

(e) S. frutescens (48 h)

(f) S. frutescens (72 h)