Acute and Subacute Toxicological Evaluation of the Aerial Extract of Monsonia angustifolia E. Mey. ex. A. Rich in Wistar Rats
Table 3
Effect of 28-day administration of Monsonia angustifolia extract on some liver function parameters of Wistar rats.
Parameters
Control
Extract (mg/kg body weight)
75
150
300
Albumin (g/dL)
16.67 ± 0.58
16.33 ± 0.06
17.07 ± 0.58
17.01 ± 0.58
Total protein (g/dL)
56.67 ± 1.51
59.67 ± 1.53
58.67 ± 1.51
57.33 ± 1.51
Total bilirubin (μmol/L)
7.00 ± 0.65
7.32 ± 0.00
7.37 ± 0.08
7.50 ± 0.54
AST (U/L)
140.33 ± 1.79
139.33 ± 1.15
141.33 ± 1.08
144.65 ± 1.71
ALT (U/L)
61.67 ± 1.02
62.67 ± 1.29
63.00 ± 1.44
63.67 ± 1.72
ALP (U/L)
380.30 ± 1.53
382.30 ± 1.15
385.00 ± 1.58
383.30 ± 1.00
GGT (U/L)
1.67 ± 0.53
1.70 ± 0.00
1.70 ± 0.00
1.67 ± 0.15
Data are means ± SEM (). Values not carrying superscripts are not significantly different () from the control. AST: aspartate aminotransferase; ALP: alkaline phosphatase; ALT: alanine aminotransferase; GGT: gamma glutamyl transferase.
