Research Article
Acute and Subacute Toxicological Evaluation of the Aerial Extract of Monsonia angustifolia E. Mey. ex. A. Rich in Wistar Rats
Table 5
Effect of 28-day administration of Monsonia angustifolia extract on the body and organ weights of rats.
| Parameters | Control | Extract (mg/kg body weight) | 75 | 150 | 300 |
| Initial body weight (g) | 283.52 ± 0.03 | 282.41 ± 0.19 | 283.33 ± 2.74 | 284.58 ± 2.87 | Final body weight (g) | 311.94 ± 0.06 | 322.28 ± 0.19 | 318.21 ± 0.86 | 333.11 ± 0.86 | Weight of liver (g) | 11.97 ± 0.20 | 12.44 ± 0.05 | 12.06 ± 0.36 | 14.99 ± 0.26 | Weight of kidney (g) | 2.33 ± 0.20 | 2.56 ± 0.06 | 2.46 ± 0.09 | 2.35 ± 0.06 | Liver-body weight ratio (%) | 3.84 ± 0.03 | 3.86 ± 0.06 | 3.79 ± 0.21 | 4.50 ± 0.01 | Kidney-body weight ratio (%) | 0.75 ± 0.02 | 0.80 ± 0.02 | 0.82 ± 0.03 | 0.78 ± 0.01 |
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Data are means ± SEM ( = 6). Values carrying superscripts are significantly different () from the control.
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