Research Article

Acute and Subacute Toxicological Evaluation of the Aerial Extract of Monsonia angustifolia E. Mey. ex. A. Rich in Wistar Rats

Table 5

Effect of 28-day administration of Monsonia angustifolia extract on the body and organ weights of rats.

ParametersControlExtract (mg/kg body weight)
75150300

Initial body weight (g)283.52 ± 0.03282.41 ± 0.19283.33 ± 2.74284.58 ± 2.87
Final body weight (g)311.94 ± 0.06322.28 ± 0.19318.21 ± 0.86333.11 ± 0.86
Weight of liver (g)11.97 ± 0.2012.44 ± 0.0512.06 ± 0.3614.99 ± 0.26
Weight of kidney (g)2.33 ± 0.202.56 ± 0.062.46 ± 0.092.35 ± 0.06
Liver-body weight ratio (%)3.84 ± 0.033.86 ± 0.063.79 ± 0.214.50 ± 0.01
Kidney-body weight ratio (%)0.75 ± 0.020.80 ± 0.020.82 ± 0.030.78 ± 0.01

Data are means ± SEM ( = 6). Values carrying superscripts are significantly different () from the control.